Tiamulin Fumarate CAS NO 55297-96-6 Inquire about Tiamulin Fumarate

Tecoland supplies Tiamulin Fumarate bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Tiamulin Fumarate is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

What is Tiamulin Fumarate?

Tiamulin (previously thiamutilin) is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.Tiamulin is a diterpene antimicrobial with a pleuromutilin chemical structure similar to that of valnemulin.

Mechanism of Action:

The mutation frequency of aflatoxin B1 could be completely inhibited by tiamulin in CYP3A4-expressing cells, but no effect was observed on the mutation frequency of the direct mutagen ethylmethanesulphonate. Western blotting of homogenates of the CYP3A4-expressing cell line showed stabilization of CYP3A4 protein after incubation with tiamulin, supporting the hypothesis that the mechanism of inhibition is by binding of tiamulin to the cytochrome.

MeSH Pharmacological Classification:

Anti-Bacterial Agents
Substances that reduce the growth or reproduction of BACTERIA.

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