Paricalcitol CAS NO 131918-61-1 Inquire about Paricalcitol 

Tecoland supplies Paricalcitol bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Paricalcitol is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is paricalcitol

Paricalcitol is a synthetic (man-made) form of vitamin D. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Paricalcitol is used to help maintain healthy levels of parathyroid hormone in people with chronic kidney disease who are on dialysis.

Paricalcitol oral is for use in adults and children at least 10 years old.

Paricalcitol injection is for use in adults and children at least 5 years old.

Paricalcitol may also be used for purposes not listed in this medication guide.

Warnings

You should not use paricalcitol if you have high levels of calcium or vitamin D in your blood.

Before taking this medicine

You should not use paricalcitol if you are allergic to it, or if you have high levels of vitamin D or calcium in your body.

You should not be treated with paricalcitol injection if you have ever had a severe allergic reaction to it.

Tell your doctor if you have ever had:

  • high blood pressure;
  • liver disease; or
  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).

Tell your doctor if you are pregnant or breastfeeding.

If you breastfeed while receiving paricalcitol injection, watch for signs of hypercalcemia in your baby (such as feeding problems, vomiting, constipation, or seizure).

How should I use paricalcitol

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Paricalcitol is usually given every other day or 3 times per week. Follow your doctor’s instructions carefully.

Paricalcitol oral is taken by mouth.

You may take paricalcitol oral with or without food.

Paricalcitol injection is given as an infusion into a vein during dialysis. A healthcare provider will give you this injection.

Tell your caregivers if you feel any burning, pain, or swelling when paricalcitol is injected.

Your blood will need to be tested often. Your doses may be delayed based on the results.

Even if you have no symptoms, tests can help your doctor determine if paricalcitol is effective.

You may need to follow a special diet while using paricalcitol. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.

Store paricalcitol oral at room temperature away from moisture, light, and heat.

Paricalcitol Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Paricalcitol may cause serious side effects. Call your doctor at once if you have:

  • fast, slow, or pounding heartbeats;
  • fever, flu symptoms, mouth and throat ulcers;
  • new or worsening cough, fever, trouble breathing;
  • a seizure; or
  • high calcium levels–nausea, vomiting, loss of appetite, constipation, increased thirst or urination, confusion, weight loss, tiredness.

You may be more likely to have a broken bone if your parathyroid hormone levels get too low. Talk with your doctor about how to avoid the risk of fractures.

Common side effects of paricalcitol may include:

  • nausea, vomiting;
  • swelling in your hands or feet;
  • dizziness or spinning sensation;
  • joint pain; or
  • runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect paricalcitol

Some medicines can make paricalcitol much less effective when taken at the same time. If you take any of the following medicines, take your oral paricalcitol dose 1 hour before or 4 to 6 hours after you take the other medicine:

  • cholestyramine; or
  • mineral oil.

Tell your doctor about all your current medicines. Many drugs can affect paricalcitol, especially:

  • digoxin (digitalis);
  • a diuretic or “water pill”;
  • nefazodone;
  • a phosphate binder–ferric citrate, sevelamer, lanthanum carbonate;
  • an antibiotic–clarithromycin, telithromycin;
  • antifungal medicine–itraconazole, ketoconazole; or
  • antiviral medicine to treat HIV/AIDS–indinavir, nelfinavir, ritonavir, saquinavir.

This list is not complete and many other drugs may affect paricalcitol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.