Loxapine Succinate CAS NO 27833-64-3 Inquire about Loxapine Succinate
Tecoland supplies Loxapine Succinate bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Loxapine Succinate is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Loxapine Succinate
Loxapine Succinate is the succinate salt form of loxapine, a tricyclic dibenzoxazepine antipsychotic agent with antiemetic, sedative, anticholinergic, and antiadrenergic actions. Loxapine succinate exerts its actions by blocking the dopamine receptors at postsynaptic receptor sites in the limbic system, cortical system and basal ganglia, thereby reducing the hallucinations and delusions that are associated with schizophrenia. This agent also exerts extrapyramidal side effects.
It is a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Chemically, it is 2-Chloro-11 (4-methyl-1-piperazinyl)dibenz[b,f][1,4] oxazepine. It is present in capsules as the succinate salt, and in the concentrate and parenteral primarily as the hydrochloride salt.
Side Effects of Loxapine
Loxapine Succinate may cause serious side effects including:
- hives,
- difficulty breathing,
- swelling of your face, lips, tongue, or throat,
- fast or uneven heart rate,
- lightheadedness,
- confusion,
- slurred speech,
- seizure,
- sudden weakness,
- ill feeling,
- fever,
- chills,
- sore throat,
- cough,
- cold or flu symptoms,
- little or no urination,
- severe constipation,
- very stiff (rigid) muscle,
- high fever,
- sweating,
- confusion, and
- tremorsGet medical help right away, if you have any of the symptoms listed above.
The most common side effects of Loxapine include:
- dizziness,
- problems with balance or walking,
- swelling in your face,
- itching,
- rash,
- tremors,
- muscle twitching,
- stiffness,
- numbness,
- weakness,
- blurred vision,
- feeling restless or agitated,
- nausea,
- vomiting,
- constipation,
- dry mouth,
- stuffy nose, and
- sleep problems (insomnia)
Tell the doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Loxapine. For more information, ask your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Disclaimer:
Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.