Ixazomib CAS NO 1072833-77-2 Inquire about Ixazomib

Tecoland supplies Ixazomib bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Ixazomib is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Ixazomib?

Ixazomib (trade name Ninlaro) is a drug for the treatment of multiple myeloma, a type of white blood cell cancer, in combination with other drugs. It is taken by mouth in form of capsules.

How does Ixazomib work?

Ninlaro (ixazomib) is the first and only oral proteasome inhibitor. Both normal cells and cancer cells contain proteasomes, enzyme complexes that break down damaged and unwanted proteins into smaller components. These smaller components are then used to create new proteins required by the cell. Proteasomes can be thought of as crucial to the cell’s “recycling” of proteins. Myeloma cells are particularly sensitive to proteasome inhibition. When their protein recycling system is shut down, myeloma cells die.

Ixazomib side effects:

People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk ofside effects. Careful monitoring by your doctor may decrease your risk.

Tell your doctor right away if you have any serious side effects, including:

• easy bruising/bleeding
• signs of infection (such as sore throat that doesn’t go away, fever, chills)
• shingles skin rash/pain (herpes zoster)
• numbness/tingling of arms/legs
• swelling hands/ankles/feet
• sudden/unexplained weight gain
• symptoms of liver disease (such as nausea/vomiting that doesn’t stop
• loss of appetite
• stomach/abdominal pain
• yellowing eyes/skin, dark urine

Ixazomib can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Get medical help right away if you develop any rash.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice any other effects not listed above, contact your doctor or pharmacist.

Ixazomib Drug Interactions:

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Other medications can affect the removal of ixazomib from your body, which may affect how ixazomib works. Examples include rifamycins (such as rifampin), St. John’s wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.


Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.