Apalutamide CAS NO 956104-40-8 Inquire about Apalutamide 

Tecoland supplies Apalutamide bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Apalutamide is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

 

What is Apalutamide?

Apalutamide is an anti-androgen. It works in the body by preventing the actions of androgens (male hormones).

Apalutamide is used to treat prostate cancer that has spread to other parts of the body (metastatic) and is also being treated with another medicine or with surgery.

Apalutamide is also used to treat prostate cancer that has not spread to other parts of the body, after surgery or other cancer treatments did not work or have stopped working.

Warnings

Although apalutamide is not for use by women, this medicine can cause birth defects if a woman is exposed to it during pregnancy.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Apalutamide dosing information

Usual Adult Dose for Prostate Cancer: 240 mg orally once a day

Comments:
-Patients should receive a gonadotropin-releasing hormone (GnRH) analog concurrently or have had a bilateral orchiectomy.

Uses:
-For the treatment of metastatic castration-sensitive prostate cancer (mCSPC)
-For the treatment of non-metastatic castration-resistant prostate cancer (nmCRPC)

Side Effects

Get emergency medical help if you have signs of an allergic reaction to apalutamide (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:

  • chest pain or discomfort (even while at rest), shortness of breath;
  • a seizure;
  • a fall; or
  • signs of a stroke – sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems.

Accidental falls may be more common in elderly patients who use apalutamide. Use caution to avoid falling or accidental injury while you are being treated with this medicine.

Common apalutamide side effects may include:

  • hot flashes;
  • diarrhea, loss of appetite;
  • weight loss;
  • tiredness;
  • falls;
  • rash;
  • joint pain;
  • increased blood pressure; or bone fractures.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.