Epirubicin HCl CAS NO 56390-09-1 Inquire about Epirubicin HCl

Tecoland supplies Epirubicin HCl bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Epirubicin HCl is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

What is Epirubicin HCl

Epirubicin HCl is the hydrochloride salt of the 4′-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation.

An anthracycline which is the 4′-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.

Biological Activity for Epirubicin HCl

Epirubicin hydrochloride is an antibiotic antitumor agent. Inhibits the synthesis and function of DNA (IC50 = 62.7 μM in rat glioblastoma cell lines) and inhibits the relaxing property of topoisomerase II.

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