Bortezomib CAS NO 154229-18-2 Inquire about Bortezomib 

Tecoland supplies Bortezomib bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Bortezomib is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Bortezomib

Bortezomib is used to treat multiple myeloma and mantle cell lymphoma.

Bortezomib may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not be treated with bortezomib if you are allergic to bortezomib, mannitol, or boron.

Tell your doctor if you have ever had:

  • nerve problems such as numbness, tingling, or burning pain;
  • diabetes;
  • liver disease;
  • kidney disease, or if you are on dialysis;
  • a low level of platelets or white or red blood cells;
  • heart disease, congestive heart failure;
  • lung disease or breathing problems;
  • herpes or shingles (herpes zoster);
  • high or low blood pressure; or
  • if you are dehydrated.

You may need to have a negative pregnancy test before starting this treatment.

Bortezomib can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.

  • If you are a woman, do not use bortezomib if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 7 months after your last dose.
  • If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
  • Tell your doctor right away if a pregnancy occurs while either the mother or the father is using bortezomib.

This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because bortezomib may harm the baby if a pregnancy does occur.

You should not breastfeed while using this medicine and for at least 2 months after your last dose.

Bortezomib Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Bortezomib may cause a serious viral infection of the brain that can lead to disability or death. Call your doctor right away if you have a severe headache, buzzing in your ears, vision problems, weakness, confusion, thinking problems, or a seizure (convulsions).

Also call your doctor at once if you have:

  • new or worsening nerve problems such as numbness, burning, pain, weakness, or tingly feeling;
  • a light-headed feeling, like you might pass out;
  • severe or ongoing nausea, vomiting, diarrhea, or constipation;
  • fever with shortness of breath or trouble breathing;
  • dehydration symptoms–feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
  • low blood cell counts–fever, chills, tiredness, flu-like symptoms, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;
  • liver problems–right-sided stomach pain, or jaundice (yellowing of the skin or eyes);
  • signs of congestive heart failure–shortness of breath (even with mild exertion), swelling in your lower legs, rapid weight gain, cough with mucus, fast heartbeats, sleep problems; or
  • signs of tumor cell breakdown–muscle cramps, tiredness, fast or slow heart rate, fluttering in your chest, decreased urination, tingling around your mouth.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects of bortezomib may include:

  • numbness or tingly feeling;
  • loss of appetite, nausea, vomiting;
  • diarrhea, constipation;
  • fever, chills, cold or flu symptoms;
  • rash; or
  • feeling tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Bortezomib drug interactions (more detail)

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.