Aprepitant CAS NO 170729-80-3 Inquire about Aprepitant 

Tecoland supplies Aprepitant bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Aprepitant is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Aprepitant

Aprepitant is used together with other medications to prevent nausea and vomiting that may be caused by chemotherapy.

Aprepitant is given ahead of time and will not treat nausea or vomiting that you already have.

Aprepitant capsules are for use in adults and children who are at least 12 years old. Aprepitant oral suspension (liquid) can be given to adults and children as young as 6 months old.

Aprepitant may also be used for purposes not listed in this medication guide.

Warnings

You should not use aprepitant if you also use pimozide. A serious drug interaction can occur when pimozide is used together with aprepitant.

Before you take Aprepitant

You should not use aprepitant if you are allergic to it, or if you use another medicine called pimozide. Aprepitant can cause unwanted or dangerous side effects when used with pimozide.

Tell your doctor if you have ever had:

  • liver disease.

Tell your doctor if you are pregnant or breastfeeding. You should not be treated with aprepitant injection if you are pregnant.

Aprepitant can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using aprepitant, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.

Keep using the barrier form of birth control for 1 month after your last dose of aprepitant.

Side Effects

Get emergency medical help if you have signs of an allergic reaction (hives, itching, difficult breathing, dizziness, trouble swallowing, fast heartbeat, wheezing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Aprepitant may cause serious side effects. Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • pain or burning when you urinate;
  • sores or white patches in your mouth or throat, sore throat;
  • low blood cell counts–fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or
  • dehydration symptoms–feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.

Common side effects of aprepitant may include:

  • stomach pain, indigestion, burping, loss of appetite;
  • low blood cell counts;
  • diarrhea, constipation;
  • hiccups;
  • abnormal liver function tests;
  • headache, dizziness;
  • dehydration;
  • pain in your arms or legs;
  • pain, hardening, redness, swelling, or itching where the medicine was injected;
  • cough; or
  • feeling weak or tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drug Interactions

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medications less effective.

Many drugs can affect aprepitant, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Aprepitant drug interactions (more detail)

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.