Otilonium bromide CAS NO 26095-59-0 Inquire about Otilonium bromide 

Tecoland supplies Otilonium bromide bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Otilonium bromide is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Otilonium bromide?Otilonium bromide

Otilonium bromide is an antimuscarinic and calcium channel blocker used to relieve spasmodic pain of the gut, especially in irritable bowel syndrome.

Medical uses

A pooled analysis of three clinical trials suggest that otilonium is more effective than placebo for the treatment of irritable bowel syndrome.

Pharmacology

Otilinium binds to both muscarinic receptors and tachykinin NK2 receptors. It has been shown to inhibit L-type and T-type calcium channels, actions which may contribute to or determine its effects in the gut.

When taken orally, very little of the drug is absorbed into the rest of the body, which means that most of its actions remain confined to the gastrointestinal system.

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

A03AB06

CAS registry number (Chemical Abstracts Service)

0026095-59-0

Chemical Formula

C29-H43-Br-N2-O4

Molecular Weight

564

Therapeutic Categories

Spasmolytic agent

Muscarinic receptor antagonist (anticholinergic, parasympatholytic agent)

Chemical Name

Etanaminium, N,N-dietyl-N-metyl-2-[[4-[[2-(octyloxy)benzoyl]amino]benzoyl]oxy]-, bromide

Foreign Names
  • Otilonii Bromidum (Latin)
  • Otilonium bromid (German)
  • Bromure d’Otilonium (French)
  • Bromuro de otilonio (Spanish)
Generic Names
  • Otilonio bromuro (OS: DCIT)
  • Otilonium Bromide (OS: BAN)
Brand Names
  • Bromotil
    Ariston, Argentina
  • Brospasmol
    Labinco, Colombia
  • Colica
    Difare, Ecuador
  • Colirid
    Zydus Cadila, India
  • Debromu
    Menarini, Mexico
  • Dismox
    Unipharm, Guatemala; Unipharm, Honduras; Unipharm, Nicaragua; Unipharm, El Salvador
  • Doralin
    A. Menarini, Cyprus; Menarini, Greece
  • Drimavin
    Rossmore Pharma, Argentina
  • Ekspaz
    Abdi Ibrahim, Turkey
  • Gispas
    Pharmactive, Georgia
  • Lonium
    Apsen, Brazil
  • Menoctyl
    Dong Wha, South Korea; Ulagaylar, Turkey
  • Motid
    Eurofarma, Argentina
  • Motigen
    Consentis, Turkey
  • Nospazm
    Pharmactive, Turkey
  • Octypasmil
    Lafedar, Argentina
  • Omuro
    Sanfer, Mexico
  • Orlix
    Garmisch, Colombia
  • Oteran
    Daewoo, South Korea
  • Otilax
    Win Medica, Greece
  • Otiliks
    Bilim, Turkey
  • Otilonio Cinfa
    Cinfa, Spain
  • Otilonio Qualigen
    Qualigen, Spain
  • Otilonio Ratiopharm
    Ratiopharm, Spain
  • Otilonio Stada
    STADA, Spain
  • Otilonio Teva
    Teva, Spain
  • Otiloteg
    Laboratorio Tecnoquímicas, Guatemala; Laboratorio Tecnoquímicas, El Salvador
  • Otylom
    Cheminter, Guatemala
  • Pasminox 40
    Beta, Argentina
  • Pasminox 40 Somatico [+ Diazepam]
    Beta, Argentina
  • Pensotil
    Pensa, Turkey
  • Piomat
    Eczane, Argentina; Pharma Roy, Peru
  • Simflat [+ Simeticone]
    Abdi Ibrahim, Turkey
  • Spadis
    Tripharma, Turkey
  • Spanol
    Santa-Farma, Turkey
  • Spasen
    Firma, Italy
  • Spasen Somatico [+ Diazepam]
    Firma, Italy
  • Spasmoctyl
    Guidotti, Spain; Menarini, Costa Rica; Menarini, Dominican Republic; Menarini, Guatemala; Menarini, Honduras; Menarini, Nicaragua; Menarini, Panama; Menarini, El Salvador
  • Spasmoctyl 40
    Nova Argentia, Argentina
  • Spasmoctyl Pediátrico [pediatric]
    Guidotti, Spain; Menarini, Costa Rica; Menarini, Dominican Republic; Menarini, Guatemala; Menarini, Honduras; Menarini, Nicaragua; Menarini, Panama; Menarini, El Salvador
  • Spasmoctyl Somatico [+ Diazepam]
    Nova Argentia, Argentina
  • Spasmodox
    Farmindustria, Peru; Laboratorios Recalcine, Chile
  • Spasmomen
    A. Menarini, Hong Kong; A. Menarini, Philippines; A. Menarini, Portugal; A. Menarini Singapore, Vietnam; Berlin-Chemie, China; Berlin-Chemie, Georgia; Berlin-Chemie, Croatia (Hrvatska); Berlin-Chemie, Slovakia; Berlin-Chemie AG, Bulgaria; Biotoscana, Peru; Dexa Medica, Indonesia; Menarini, Belgium; Menarini, Ecuador; Menarini, Egypt; Menarini, Israel; Menarini, Lebanon; Menarini, Lithuania; Menarini, Latvia; Menarini, Tunisia; Menarini Industrie Farmaceutiche Riunite, Italy; Menarini Industrie Farmaceutiche Riunite, Romania; Menarini International, Malta; Menarini International Operations Luxembourg S.A., Hungary; UFSA, Turkey
  • Spasmomen [+ Diazepam]
    Menarini Industrie Farmaceutiche Riunite, Italy
  • Spasmomen 40mg
    Menarini, Luxembourg
  • Spastop
    Teriak, Tunisia
  • Spazmodin
    Dincsa Ilac, Turkey
Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.

External Link:
  1. Wikipedia contributors. (2020, December 2). Otilonium bromide. Wikipedia. https://en.wikipedia.org/wiki/Otilonium_bromide
  2. Otilonium Bromide. (n.d.). Drugs.Com. https://www.drugs.com/international/otilonium-bromide.html