Salmeterol Xinafoate Propionate + Fluticasone propionate CAS NO 136112-02-2 Inquire about Salmeterol Xinafoate Propionate + Fluticasone propionate 

Tecoland supplies Salmeterol Xinafoate Propionate + Fluticasone propionate bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Salmeterol Xinafoate Propionate + Fluticasone propionate is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Salmeterol Xinafoate Propionate + Fluticasone propionate

Fluticasone and salmeterol is a combination of two medicines that are used to help control the symptoms of asthma and improve breathing. It is used when a patient’s asthma has not been controlled sufficiently on other asthma medicines, or when a patient’s condition is so severe that more than one medicine is needed every day. This medicine will not relieve an asthma attack that has already started.

This medicine is also used to treat air flow blockage and reduce the worsening of chronic obstructive pulmonary disease (COPD). This includes chronic bronchitis and emphysema.

Inhaled fluticasone belongs to the family of medicines known as corticosteroids or steroids (cortisone-like medicines). It works by preventing certain cells in the lungs and breathing passages from releasing substances that cause asthma symptoms.

Inhaled salmeterol is a long-acting bronchodilator. Bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. It relieves cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine must be used with a short-acting medicine (eg, albuterol) for an asthma attack or asthma symptoms that need attention right away.

Warnings

Fluticasone and salmeterol is not a rescue medicine. It will not work fast enough to treat an asthma or bronchospasm attack.

Seek medical attention you have worsening breathing problems, or if you think your medications are not working as well.

Before taking this medicine

You should not use fluticasone and salmeterol if you are allergic to fluticasone or salmeterol, or:

  • if you have a severe allergy to milk proteins; or
  • if you are having an asthma attack or severe COPD symptoms.

Fluticasone can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks.

Tell your doctor if you have ever had:

  • glaucoma or cataracts;
  • heart disease or high blood pressure;
  • a seizure;
  • diabetes;
  • a food or drug allergy;
  • a weak immune system;
  • any type of infection (bacterial, fungal, viral, or parasitic);
  • osteoporosis;
  • a thyroid disorder; or
  • liver or kidney disease.

Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis. Talk with your doctor about your risk.

Tell your doctor if you are pregnant. It is not known whether this medicine will harm an unborn baby. However, having untreated or uncontrolled asthma during pregnancy may cause complications such as low birth weight, premature birth, or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating asthma may outweigh any risks to the baby.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Do not give this medicine to a child without medical advice.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Fluticasone and salmeterol may cause serious side effects. Call your doctor at once if you have:

  • wheezing, choking, or other breathing problems after using fluticasone and salmeterol;
  • fever, chills, cough with mucus, feeling short of breath;
  • chest pain, fast or irregular heartbeats, severe headache, pounding in your neck or ears;
  • tremors, nervousness;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • signs of thrush (a fungal infection)–sores or white patches in your mouth or throat, trouble swallowing;
  • high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor;
  • low potassium level–leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; or
  • signs of a hormonal disorder–worsening tiredness or weakness, feeling light-headed, nausea, vomiting.

Fluticasone can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Common side effects of fluticasone and salmeterol may include:

  • headache, muscle pain, bone pain, back pain;
  • nausea, vomiting;
  • thrush, throat irritation;
  • ongoing cough, hoarseness or deepened voice;
  • cold symptoms such as stuffy nose, sneezing, sore throat; or
  • ear infection (in a child)–fever, ear pain or full feeling, trouble hearing, drainage from the ear, fussiness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drug Interactions

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your other medicines, especially:

  • antifungal medicine; or
  • medicine to treat HIV or AIDS.

This list is not complete and many other drugs may affect fluticasone and salmeterol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.