Fluvastatin Sodium CAS NO 93957-54-1 Inquire about Fluvastatin Sodium
Tecoland supplies Fluvastatin Sodium bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Fluvastatin Sodium is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Fluvastatin Sodium
Fluvastatin Sodium is the sodium salt of a synthetic lipid-lowering agent with potential antineoplastic activity. Fluvastatin competitively inhibits hepatic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses through the suppression of MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. Through the inhibition of mevalonate synthesis, statins, like fluvastatin, have been shown to inhibit the production of dolichol, geranylpyrophosphate (GPP) and farnesylpyrophosphate (FPP) and the isoprenylation of the intracellular G-proteins Ras and Rho, which may result in antiangiogenic, apoptotic, and antimetastatic effects in susceptible tumor cell populations.
Fluvastatin Sodium Side Effects
It may cause serious side effects including:
- hives,
- difficulty breathing,
- swelling of your face, lips, tongue, or throat,
- little or no urinating,
- painful or difficult urination,
- swelling in your feet or ankles,
- tiredness,
- shortness of breath,
- upper stomach pain,
- loss of appetite,
- dark urine,
- clay-colored stools, and
- yellowing of the skin or eyes (jaundice)
- tiredness,
Get medical help right away, if you have any of the symptoms listed above.
The most common side effects of Lescol include:
- muscle pain,
- headache,
- stomach pain,
- nausea, and
- indigestion
Disclaimer:
Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.