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Busulfan
Description
Busulfan
belongs to the group of medicines known as alkylating agents.
It is used to treat some kinds of cancer of the blood. It may
also be used as a conditioning regimen prior to progenitor
cell transplantation for treatment of chronic myelogenous
leukemia.
Busulfan seems
to act by interfering with the function of the bone marrow.
Since the growth of normal body cells may also be affected by
busulfan, other effects will also occur. Some of these may be
serious and must be reported to your doctor. Other effects may
not be serious but may cause concern. Some effects may not
occur for months or years after the medicine is used.
Side Effects
of Busulfan
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Black, tarry stools; blood in urine or
stools; cough or hoarseness; fever or chills;
inflammation of the mouth; lower back or side pain;
painful or difficult urination; pinpoint red spots on
skin; unusual bleeding or bruising
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Chest pain; dizziness; fast or irregular
breathing; joint pain ; light-headedness; puffiness or
swelling around face; rapid heartbeat; shortness of
breath; sudden, severe decrease in blood pressure;
sweating; swelling of fingers, hands, arms, lower legs, or
feet; sweating; tingling in lower legs, hands, or feet
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Blurred vision; difficulty swallowing ;
heartburn; severe upper abdominal and back pain; vomiting
blood
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Abdominal pain; anxiety; diarrhea; general
fatigue or muscle pain; headache; missed or irregular
menstrual periods; loss of appetite; nausea and vomiting;
rash; trouble in sleeping; weight loss (sudden)
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Bloody nose; confusion; constipation;
darkening of skin; depression; dry mouth; inflammation at
place of injection; itching; sore throat or cough; stuffy
nose, runny nose, or sneezing
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Because of the way these medicines act on the
body, there is a chance that they might cause other unwanted
effects that may not occur until months or years after the
medicine is used. These delayed effects may include certain
types of cancer, such as leukemia.
Precautions while taking Bulsulfan
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If you can, avoid people with infections.
Check with your doctor immediately if you think you are
getting an infection or if you get a fever or chills, cough
or hoarseness, lower back or side pain, or painful or
difficult urination.
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Check with your doctor immediately
if you notice any unusual bleeding or bruising; black, tarry
stools; blood in urine or stools; or pinpoint red spots on
your skin.
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Be careful when using a regular toothbrush,
dental floss, or toothpick. Your medical doctor, dentist, or
nurse may recommend other ways to clean your teeth and gums.
Check with your medical doctor before having any dental work
done.
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Do not touch your eyes or the inside of your
nose unless you have just washed your hands and have not
touched anything else in the meantime.
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Be careful not to cut yourself when you are
using sharp objects such as a safety razor or fingernail or
toenail cutters.
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Avoid contact sports or other situations
where bruising or injury could occur.
Disclaimer:
Information on this page is provided for general
information purposes. You should not make a clinical treatment
decision based on information contained in this page without
consulting other references including the package insert of
the drug, textbooks and where relevant, expert opinion. We
cannot be held responsible for any errors you make in
administering drugs mentioned on this page, nor for use of any
erroneous information contained on this page.
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