Dactinomycin CAS NO 50-76-0 Inquire about Dactinomycin

Tecoland supplies Dactinomycin bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Dactinomycin is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Dactinomycin used for?Dactinomycin

Dactinomycin is used to treat testicular cancer, sarcomas (cancers that grow from cartilage, fat, muscle, or bone), and other types of cancer.

How does Dactinomycin work?

Dactinomycin is one of a large group of drugs known as “antineoplastics”; these drugs are also known as cancer drugs, chemotherapy, or “chemo”. They are used in the treatment of various cancers to slow or stop the growth of cancer cells. A combination of different types of cancer drugs will often be used to achieve better results and minimize side effects.Dactinomycin is in the group of chemotherapy drugs known as antibiotics. It stops cancer cells, from growing, causing them to die.

How to use Dactinomycin

Use Dactinomycin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Dactinomycin is usually given as an injection at your doctor’s office, hospital, or clinic. Ask your doctor or pharmacist any questions you may have about Dactinomycin .
  • If you get Dactinomycin in your eyes or on your skin, rinse the area with water for 15 minutes. Remove any contaminated clothing and do not reuse. Contaminated shoes must be cleaned completely before reuse.
  • If you miss a dose of Dactinomycin , contact your doctor right away.
    Ask your health care provider any questions you may have about how to use Dactinomycin.
Do not use Dactinomycin if:
  • you are allergic to any ingredient in Dactinomycin
  • you have chickenpox (varicella infection), or shingles (herpes zoster infection), or if you have had either of these infections recently
  • Contact your doctor or health care provider right away if any of these apply to you.
How to administer Dactinomycin?

Dactinomycin is given as a injection in a vein over about 15 minutes. Tell the if you feel pain, burning, or discomfort in the vein when the medicine is given. You will get medicine before the dactinomycin and to take afterward to stop any nausea or vomiting. The dose and how often you get the medicine depends upon your size, your blood counts, and the type of cancer you are being treated for. You will have your blood counts and other lab work checked before each treatment; if the results are outside the range of safety, your treatment will be delayed. You may be given other anti-cancer medicines in addition to this one.

Dactinomycin may also be used to treat a local area of cancer by infusing it into the artery that supplies the cancerous area with blood. The side effects depend on how much of the drug is absorbed into the body.


This drug is given into the vein (IV). If the drug leaks out of the vein and under the skin, it may damage the tissue, causing pain, ulceration, and scarring. Tell the right away if you notice redness, pain, or swelling at or near the IV.

Dactinomycin is very toxic. If it is given at home, it must be handled very carefully. Avoid inhaling the powder or liquid, allowing contact with your skin, or getting it near your face. Talk with your doctor or about specific safety instructions.

Your doctor will probably test your blood throughout your treatment, looking for possible effects of the drug on blood counts (described below) or on other body organs. Based on the test results, you may be given medicines to help treat any effects. Your doctor may also need to reduce or delay your next dose of this drug, or even stop it altogether.

Dactinomycin can lower your white blood cell count, especially in the weeks after the drug is given. This can increase your chance of getting an infection. Be sure to let your doctor or know right away if you have any signs of infection, such as fever (100.5?or higher), chills, pain when passing urine, a new cough, or bringing up sputum.

This drug may lower your platelet count in the weeks after it is given, which can increase your risk of bleeding. Talk with your doctor before taking any drugs or supplements that might affect your body’s ability to stop bleeding, such as aspirin or aspirin-containing medicines, warfarin (Coumadin), or vitamin E. Tell your doctor right away if you have unusual bruising, or bleeding such as nosebleeds, bleeding gums when you brush your teeth, or black, tarry stools.

Dactinomycin may lower your red blood cell count. If this occurs, it is usually a few months after starting treatment. A low red blood cell count (known as anemia) can cause shortness of breath, or make you to feel weak or tired all the time. Your doctor may give you medicines to help prevent or treat this condition, or you may need to get blood transfusions.

Do not get any immunizations (vaccinations), either during or after treatment with this drug, without your doctor’s OK. This drug may affect your immune system, which could make vaccinations ineffective, or could even lead to serious infections. Try to avoid contact with people who have recently received a live virus vaccine, such as the oral polio vaccine or smallpox vaccine. Check with your doctor about this.

You may have nausea and vomiting on the day you receive this drug or in the first few days afterward. Your doctor may give you medicine before your treatment to help prevent nausea and vomiting. You will probably also get a prescription for an anti-nausea medicine that you can take at home. It is important to have these medicines on hand and to take them as prescribed by your doctor.

This drug may cause hair loss. You may want to talk to your doctor or about getting a wig before starting treatment. If your insurance does not cover it, there may be other resources to help you. Hair loss is usually temporary, and your hair will probably grow back during or after treatment.

Dactinomycin can cause radiation recall. When a person receives this drug, the skin or tissue damage from prior radiation therapy can become red and appear damaged again. Tell your doctor or if your skin gets red in areas where radiation was given.


Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.