Ansamitocin P-3 CAS NO 66547-09-9 Inquire about Ansamitocin P-3
Tecoland supplies Ansamitocin P-3 bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Ansamitocin P-3 is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Ansamitocin P-3?
Ansamitocin P-3 is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. It shares the same binding site as rhizoxin and phomopsin A on porcine brain tubulin. Maytansine and its analogs cause extensive disassembly of the microtubule and totally prevent tubulin spiralization. Ansamitocin P-3 is a fungal metabolite with antimitotic, antimitotic activity. Ansamitocin P-3 binds to tubulin and inhibits vinblastine-induced spiral formation.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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