Afoxolaner CAS NO 1093861-60-9 Inquire about Afoxolaner

Tecoland supplies Afoxolaner bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Afoxolaner is manufactured by cGMP compliant facility. Welcome to contact us for further details including the current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

What is Afoxolaner?

Afoxolaner is used to treat and prevent flea and tick infestations in dogs. It is also used as a prevention for Lyme disease. After being ingested by a dog, afoxolaner is distributed throughout the dog’s body. When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal.

Sometimes afoxolaner is used for the treatment of sarcoptic mange, demodectic mange, cutaneous myiasis, ear mite infestations and, sand fly infestations in dogs. It is also occasionally used in cats to treat ear mites and in birds to treat Peacock louse. When afoxolaner is prescribed in these cases, it is referred to as ‘extra-label’ or ‘off-label’ use. Many drugs are commonly prescribed for off-label use in veterinary medicine. In these instances, follow your veterinarian’s directions and cautions very carefully, as their directions may be significantly different from those on the manufacturer’s label.

Potential Side Effects

Most dogs have very few side effects from afoxolaner, provided it is given according to label recommendations and at the prescribed interval (or for off-label use, according to the directions given by your veterinarian). If you observe any vomiting, dry/flaky skin, diarrhea, lethargy, lack of appetite, or neurological signs such as incoordination, muscle tremors, or seizures, contact your veterinarian. At that time, make sure your veterinarian is aware of any other medications or natural remedies that you give your dog.

Risk Factors

Afoxolaner should be used with caution in dogs with a history of seizures. Do not use it in pets that are allergic to it. Do not use it in dogs less than eight weeks of age or that weigh less than four pounds (1.8kg) unless instructed by your veterinarian.

Afoxolaner has not been evaluated in breeding, pregnant, or lactating dogs.

Drug Interactions

At this time, there are no known drug interactions reported with afoxolaner. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking.

Storage Instruction

Store afoxolaner-based products at room temperature (below 30°C or 86°F) in a cool, dry place, away from heat.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.